I found an interesting fanfic about Pinkie sense once. Was submitted on EqD, a Twipie fic which generally don't interest me (it has grown on me now). How do you make stuff like this anyway? I am trying to learn about different types of animation for various personal projects I have on my mind constantly.
Explaining exactly how I make a sprite would take a lot of time. One of the many ways is basically shrink down a picture and make it look good small. explanation of what I mean by that:[link] Next determine what needs to move in the picture to get the motion you want. Use references like body and surrounding objects, videos etc. Then start drawing the transition frames making sure not to move the parts too far or else it will be kind of jerky looking. I usually use the marquee or lasso tool to move the main parts where I want them to be, then redraw so they are in the correct position ie did they need to rotate some, would they elongate, scrunch up? Continue on til you have your animation. Check the animation out. Look at different areas, even those that are not moving to see if they needed to, then the thing as a whole. If you are satisfied have someone else check it out and there you have your sprite. There's a lot more tips depending on the type of sprite you want to make but this is the basics of it. Pay attention to colors, how light would effect them. Read through a few spriting tutorials online and you'll find people go about the task in a few different ways. Try a few and find what works for you. Good luck and wish I could explain it better but it would probably take me writing a paper with some examples to make it better.